While topical treatments are often preferred for skin conditions like psoriasis, current treatments of moisturizing and scale removal may not be enough. Compounded topical prescriptions like sirolimus may offer a more effective treatment without systemic side effects. Treatment of psoriasis with topical sirolimus: preclinical development and a randomized, double-blind trial.
Rosacea treatment can include trigger avoidance, oral antibiotics, and surgery if severe. Each of these treatments can be ineffective or undesirable due to side effects. A topical treatment may be a better method of treatment for some patients. A randomized, double-blind, placebo-controlled, pilot study to assess the efficacy and safety of clindamycin 1.2% and tretinoin 0.025% combination gel for the treatment of acne rosacea over 12 weeks.
Scarring and Keloids
Current treatments to remove scars and keloids are often ineffective and can leave behind damage or discoloration of their own. The use of chemotherapy agents like tamoxifen has shown successful results in decreasing the growth of keloids without the side effects of other treatments. Tamoxifen downregulates TGF-beta production in keloid fibroblasts.
Reversing and preventing the visible aging of skin is a major concern for many adults. These signs can be from normal aging or excessive sun exposure. Regardless of the cause compounded treatments can offer treatments not found elsewhere. Treatment of skin aging with topical estrogens.
Randomized, placebo-controlled, double blind study on the clinical efficacy of a cream containing 5% alpha-lipoic acid related to photoageing of facial skin.
Vitiligo is currently very difficult to treat with current treatment methods often being ineffective. Treatment with pseudocatalase and UVB exposure has shown to both repigment skin that has been affected and new areas from being effected. Treatment of vitiligo with a topical application of pseudocatalase and calcium in combination with short-term UVB exposure: a case study on 33 patients.